Our mission is to pursue excellence in research in the prevention, treatment and training of HIV and related diseases. The DTHF aims to impact health policy through both clinical and operational research by way of accredited peer-reviewed publications, guidance to local and national government, and community education and feedback. The DTHF health services and implementation research include vaccine research, scale up of community HIV treatment, behavioural research, community based disease screening, a major project on TB transmission, diagnostics, treatment adherence, training of health professionals in HIV and TB management, and a range of novel HIV preventative research in young women, adolescents, and key populations. Our public benefit status enables us to raise money for additional community projects such as our mobile units and a youth wellness centre.